Search results for "Prostaglandins A"

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Hidradenitis Suppurativa in a Large Cohort of Italian Patients: Evaluation of the Burden of Disease

2022

<b><i>Background:</i></b> Hidradenitis suppurativa (HS) is a chronic, inflammatory, recurrent, debilitating skin disease of the hair follicle that usually occurs after puberty with painful, deep-seated, inflamed nodules and sinus tracts in the apocrine gland-bearing areas of the body, most commonly the axillae and inguinal and anogenital regions, with a relevant impact on patients’ quality of life (QoL). <b><i>Objective:</i></b> To evaluate how the burden of HS disease impacts on patient well-being and working activities in a large Italian population over a period of 9 months. <b><i>Methods:</i></b> A multicenter, prosp…

Burden of diseaseAdultMalemedicine.medical_specialtyHIDRAdiskDermatologyDiseaseSeverity of Illness IndexBurden of disease; HIDRAdisk; Hidradenitis suppurativa; Quality of lifeCohort StudiesYoung AdultQuality of lifeCost of IllnessInternal medicinemedicineHumansHidradenitis suppurativaProspective StudiesStage (cooking)Disease burdenQuality of life.Prostaglandins Abusiness.industryBurden of diseaseDermatology Life Quality IndexMiddle Agedmedicine.diseaseCost of IllneProspective StudieHidradenitis suppurativaItalyQuality of LifeFemaleCohort StudiebusinessCohort studyHuman
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Prostaglandin A2 (PGA2) increases the coronary vascular resistance in the guinea-pig isolated heart preparation.

1977

Prostaglandin A2 (PGA2) in concentrations of 1.5·10−8 to 3·10−6 M was found to produce concentration-dependent increase in the coronary vascular resistance of the guinea-pig isolated heart without alterations in myocardial contractile force and oxygen consumption.

Isolated Heart PreparationMalemedicine.medical_specialtyGuinea PigsProstaglandinPharmacologyGuinea pigCellular and Molecular Neurosciencechemistry.chemical_compoundInternal medicinemedicineAnimalsMolecular BiologyPharmacologyProstaglandins ADose-Response Relationship Drugbusiness.industryCell BiologyIsolated heartCoronary VesselsMyocardial Contractionmedicine.anatomical_structurechemistryVascular resistanceCardiologyMolecular MedicineFemaleVascular ResistancebusinessExperientia
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